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Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy and Safety of Certolizumab Pegol in Subjects With Active Axial Spondyloarthritis

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Trial Profile

Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy and Safety of Certolizumab Pegol in Subjects With Active Axial Spondyloarthritis

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 25 Apr 2025

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At a glance

  • Drugs Certolizumab pegol (Primary)
  • Indications Ankylosing spondylitis; Axial spondyloarthritis; Non-radiographic axial spondyloarthritis
  • Focus Registrational; Therapeutic Use
  • Acronyms RAPID-axSpA
  • Sponsors UCB; UCB Biosciences

Most Recent Events

  • 03 Jun 2023 Results of post hoc analysis assessing relationship between objective signs of inflammation (OSI), as measured by MRI/CRP, and clinical outcomes following 12 weeks of CZP treatment in pts with active axSpA presented at the 24th Annual Congress of the European League Against Rheumatism
  • 14 Nov 2022 Results of post hoc analysis assessing relationship between objective signs of inflammation as measured by MRI/CRP and clinical outcomes presented at the ACR Convergence 2022
  • 15 Nov 2021 Results of post-hoc sub-study assessing whether TNFi treatment over 4 years impacts fat lesions in spinal vertebral edges in patients with axSpA stratified by axSpA subpopulation (r-axSpA/nr-axSpA) or disease duration years published in the Rheumatology

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