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Evaluation of Sorafenib in Combination With Local Micro-therapy Guided by Gd-EOB-DTPA Enhanced MRI in Patients With Inoperable Hepatocellular Carcinoma

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Trial Profile

Evaluation of Sorafenib in Combination With Local Micro-therapy Guided by Gd-EOB-DTPA Enhanced MRI in Patients With Inoperable Hepatocellular Carcinoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 22 Aug 2022

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At a glance

  • Drugs Sorafenib (Primary) ; Gadoxetate disodium; Yttrium-90
  • Indications Liver cancer
  • Focus Therapeutic Use
  • Acronyms SORAMIC

    • Most Recent Events

    • 15 Aug 2022 Results of post-hoc analysis assessing prognostic value of gadoxetic acid uptake on hepatobiliary phase MRI in patients with advanced HCC receiving sorafenib, published in the Journal of Cancer Research and Clinical Oncology.
    • 26 Aug 2021 Results (n=282) assessing the outcome of patients receiving selective internal radiation therapy (SIRT) + sorafenib versus sorafenib alone was affected by adverse effects of SIRT on liver function, published in the Journal of Hepatology.
    • 14 Aug 2019 Results comparing the efficacy and safety of a combination of selective internal radiotherapy (SIRT) with yttrium-90 ((90)Y) resin microspheres and sorafenibin patients with advanced HCC published in the Journal of Hepatology

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