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A Randomized, Placebo-controlled, Two-period, Two-treatment, Two Sequence, Cross-over Pharmacodynamic and Pharmacokinetic Interaction Study After 5-days Repeated Oral Doses of Clopidogrel (600 mg Loading Dose Followed by 150 mg/Day) Alone or Given Concomitantly With Omeprazole 80 mg/Day in Healthy Male and Female Subjects.

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Trial Profile

A Randomized, Placebo-controlled, Two-period, Two-treatment, Two Sequence, Cross-over Pharmacodynamic and Pharmacokinetic Interaction Study After 5-days Repeated Oral Doses of Clopidogrel (600 mg Loading Dose Followed by 150 mg/Day) Alone or Given Concomitantly With Omeprazole 80 mg/Day in Healthy Male and Female Subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Jan 2020

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At a glance

  • Drugs Clopidogrel (Primary) ; Omeprazole (Primary)
  • Indications Acute coronary syndromes; Angina pectoris; Atherosclerosis; Cardiovascular disorders; Duodenal ulcer; Dyspepsia; Embolism and thrombosis; Gastric ulcer; Gastritis; Gastro-oesophageal reflux; Helicobacter infections; Ischaemic heart disorders; Myocardial infarction; Peptic ulcer; Peripheral arterial occlusive disorders; Stroke; Unstable angina pectoris; Zollinger-Ellison syndrome
  • Focus Pharmacodynamics
  • Sponsors Sanofi

Most Recent Events

  • 27 Aug 2010 Trial phase changed from IV to I as reported by ClinicalTrials.gov.
  • 29 May 2010 New trial record

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