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An Open-label, Single-arm, Phase I/II Study of Lapatinib in Combination With Weekly Paclitaxel as First-line Chemotherapy for ErbB2-overexpressing Metastatic Breast Cancer Patients.

Trial Profile

An Open-label, Single-arm, Phase I/II Study of Lapatinib in Combination With Weekly Paclitaxel as First-line Chemotherapy for ErbB2-overexpressing Metastatic Breast Cancer Patients.

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 03 Jul 2023

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At a glance

  • Drugs Lapatinib (Primary) ; Paclitaxel
  • Indications Advanced breast cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors GlaxoSmithKline; GSK

Most Recent Events

  • 18 Sep 2014 The Primary endpoint assessment (OS) duration changes from "assumption of 2 yrs" to "until death due to any cause or study close, whichever occurred first (assessed up to a maximum of 1290 Days)" according to ClinicalTrials.gov
  • 30 May 2014 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
  • 01 Feb 2013 Planned End Date changed from 1 Mar 2013 to 1 Jun 2014 as reported by ClinicalTrials.gov.

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