Trial Profile

A Phase I Study of the PARP Inhibitor ABT-888 in Combination With Temozolomide in Acute Leukemias

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 13 Mar 2025

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At a glance

Drugs Temozolomide (Primary) ; Veliparib (Primary)
Indications Acute myeloid leukaemia; Acute promyelocytic leukaemia; Chronic myeloid leukaemia; Chronic myelomonocytic leukaemia; Precursor B-cell lymphoblastic leukaemia-lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma; Precursor T-cell lymphoblastic leukaemia-lymphoma
Focus Adverse reactions

Most Recent Events

11 Mar 2025 Planned End Date changed from 22 Feb 2025 to 22 Feb 2026.
08 Dec 2015 Results (n=49) presented at the 57th Annual Meeting and Exposition of the American Society of Hematology.
17 Jul 2013 Planned end date changed from 1 Jun 2013 to 1 Oct 2013 as reported by ClinicalTrials.gov.

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