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An Open-label, Multiple Ascending Dose (MAD) Study of the Selective BRAF Inhibitor RO5212054 (PLX3603) to Evaluate Safety, Tolerability and Pharmacokinetics in Patients With BRAF V600-mutated Advanced Solid Tumours

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An Open-label, Multiple Ascending Dose (MAD) Study of the Selective BRAF Inhibitor RO5212054 (PLX3603) to Evaluate Safety, Tolerability and Pharmacokinetics in Patients With BRAF V600-mutated Advanced Solid Tumours

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs RG 7256 (Primary)
  • Indications Colorectal cancer; Malignant melanoma; Solid tumours
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Sponsors Roche

    • Most Recent Events

    • 13 Mar 2017 Status changed from active, no longer recruiting to completed.
    • 01 Sep 2016 Planned End Date changed from 1 Sep 2016 to 1 Oct 2016.
    • 01 Sep 2016 Planned primary completion date changed from 1 Sep 2016 to 1 Oct 2016.

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