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An open-label, randomized, 4-treatment, 3-period, crossover interaction study, evaluating the effect of esomeprazole 40 mg, omeprazole 80 mg or lansoprazole 60 mg on the pharmacodynamics and the pharmacokinetics of clopidogrel in healthy volunteers

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An open-label, randomized, 4-treatment, 3-period, crossover interaction study, evaluating the effect of esomeprazole 40 mg, omeprazole 80 mg or lansoprazole 60 mg on the pharmacodynamics and the pharmacokinetics of clopidogrel in healthy volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Jan 2016

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At a glance

  • Drugs Esomeprazole (Primary) ; Lansoprazole (Primary) ; Omeprazole (Primary) ; Clopidogrel
  • Indications Bleeding ulcer; Duodenal ulcer; Dyspepsia; Gastric ulcer; Gastritis; Gastro-oesophageal reflux; Helicobacter infections; NSAID-induced ulcer; Peptic ulcer; Reflux oesophagitis; Zollinger-Ellison syndrome
  • Focus Pharmacodynamics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 28 Mar 2014 Results published in the American Journal of Cardiovascular Drugs.
    • 27 Jun 2011 Actual end date (May 2011) added as reported by ClinicalTrials.gov.
    • 27 Jun 2011 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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