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A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalating, Phase 2a Safety, Tolerability, and Pharmacodynamic Study of Two Doses of an Histone Deacetylase Inhibitor (FRM-0334) in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation

Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalating, Phase 2a Safety, Tolerability, and Pharmacodynamic Study of Two Doses of an Histone Deacetylase Inhibitor (FRM-0334) in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs FRM 0334 (Primary)
  • Indications Dementia; Neurodegenerative disorders
  • Focus Adverse reactions; Pharmacodynamics
  • Sponsors FORUM Pharmaceuticals
  • Most Recent Events

    • 10 Apr 2017 This trial has been completed in united kingdom (end date: 2016-06-24) according to European Clinical Trials Database record.
    • 04 Oct 2016 This trial was completed in Netherlands, according to European Clinical Trials Database.
    • 30 Jul 2016 This trial was completed in Belgium (end date: 2016-07-24) according to European Clinical Trials Database record.
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