A Randomized Phase Ib/II Study of Preoperative GDC-0449 and Androgen Ablation Compared to Androgen Ablation Alone Followed by Radical Prostatectomy for Select Patients With Locally Advanced Adenocarcinoma of the Prostate.
Phase of Trial: Phase I/II
Latest Information Update: 26 Apr 2018
At a glance
- Drugs Vismodegib (Primary) ; Goserelin; Leuprorelin
- Indications Adenocarcinoma; Prostate cancer
- Focus Therapeutic Use
- 20 Apr 2018 Status changed from active, no longer recruiting to discontinued.
- 10 Jun 2017 Biomarkers information updated
- 08 Sep 2015 Planned primary completion date changed from 1 May 2020 to 1 Jan 2020 as reported by ClinicalTrials.gov