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An Open-Label Study to Assess the Effect of Multiple-Dose JNJ26489112 on the Cytochrome P450 Enzymes Using a 3-Probe Substrate Drug Combination in Healthy Subjects.

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Trial Profile

An Open-Label Study to Assess the Effect of Multiple-Dose JNJ26489112 on the Cytochrome P450 Enzymes Using a 3-Probe Substrate Drug Combination in Healthy Subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs JNJ 26489112 (Primary) ; Midazolam; Omeprazole; Tolbutamide
  • Indications Anxiety; Diabetes mellitus; Duodenal ulcer; Dyspepsia; Epilepsy; Gastro-oesophageal reflux; Helicobacter infections; Insomnia; Major depressive disorder; Peptic ulcer; Zollinger-Ellison syndrome
  • Focus Pharmacokinetics
  • Sponsors Janssen Research & Development

Most Recent Events

  • 19 Mar 2012 Actual initiation date changed from Jul 2010 to Jun 2010 as reported by ClinicalTrials.gov.
  • 19 Mar 2012 Additional location (USA) added as reported by ClinicalTrials.gov.
  • 07 Oct 2010 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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