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A Randomised Controlled Trial of Pneumococcal Conjugate Vaccines Synflorix and Prevenar13 in Sequence or Alone in High-risk Indigenous Infants (PREV-IX-COMBO): Immunogenicity, Carriage and Otitis Media Outcomes.

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Trial Profile

A Randomised Controlled Trial of Pneumococcal Conjugate Vaccines Synflorix and Prevenar13 in Sequence or Alone in High-risk Indigenous Infants (PREV-IX-COMBO): Immunogenicity, Carriage and Otitis Media Outcomes.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 20 Sep 2022

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At a glance

Most Recent Events

  • 01 Sep 2022 Results (n=261; Between April 10, 2013, and Sept 4, 2018) assessing the immunogenicity of novel pneumococcal conjugate vaccine (PCV) schedules from PREVIX_COMBO and PREVIX_BOOST randomised controlled trials, published in The Lancet Infectious Diseases.
  • 23 Mar 2021 Primary endpoint of he proportion of nasopharyngeal (Np) swabs positive for PCV13 at 7 months has not been met, according to results published in the Vaccine.
  • 23 Mar 2021 Results published in the Vaccine

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