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The Effect of Phenytoin on the Pharmacokinetics of Nevirapine and the Development of Nevirapine Resistance After a Single Dose Nevirapine (VIramune), Which is Part of ARV Prophylaxis for PMTCT in Moshi, TAnzania, and in Lusaka, Zambia (VITA2 Trial).

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Trial Profile

The Effect of Phenytoin on the Pharmacokinetics of Nevirapine and the Development of Nevirapine Resistance After a Single Dose Nevirapine (VIramune), Which is Part of ARV Prophylaxis for PMTCT in Moshi, TAnzania, and in Lusaka, Zambia (VITA2 Trial).

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 09 Feb 2022

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At a glance

  • Drugs Nevirapine (Primary) ; Phenytoin (Primary) ; Lamivudine; Lamivudine/zidovudine; Zidovudine
  • Indications HIV infections
  • Focus Pharmacokinetics
  • Acronyms VITA2

    • Most Recent Events

    • 17 Jul 2013 Primary endpoint 'Pharmacokinetic-parameters' has been met, according to the Journal of Antimicrobial Chemotherapy.
    • 17 Jul 2013 Primary endpoint 'Drug-elimination-half-life' has been met, according to the Journal of Antimicrobial Chemotherapy.
    • 17 Jul 2013 Primary endpoint 'Antiretroviral-resistance' has been met, according to the Journal of Antimicrobial Chemotherapy.

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