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Genetic Events Leading to APC-Dependent Colon Cancer in High-Risk Families; a Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients

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Trial Profile

Genetic Events Leading to APC-Dependent Colon Cancer in High-Risk Families; a Clinical Trial of COX and EGFR Inhibition in Familial Polyposis Patients

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 18 May 2022

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At a glance

  • Drugs Erlotinib (Primary) ; Sulindac (Primary)
  • Indications Familial adenomatous polyposis
  • Focus Therapeutic Use

    • Most Recent Events

    • 13 Apr 2022 Results presented at the 113th Annual Meeting of the American Association for Cancer Research
    • 22 Mar 2016 Status changed from active, no longer recruiting to completed according to results published in the Journal of the American Medical Association.
    • 22 Mar 2016 Primary endpoint of comparison of change in total duodenal and colorectal polyp burden at 6 months has been met, according to results published in the Journal of the American Medical Association.

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