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A Randomized Phase III Study to Compare Bortezomib, Melphalan, Prednisone (VMP) With High Dose Melphalan Followed by Bortezomib, Lenalidomide, Dexamethasone (VRD) Consolidation and Lenalidomide Maintenance in Patients With Newly Diagnosed Multiple Myeloma

Trial Profile

A Randomized Phase III Study to Compare Bortezomib, Melphalan, Prednisone (VMP) With High Dose Melphalan Followed by Bortezomib, Lenalidomide, Dexamethasone (VRD) Consolidation and Lenalidomide Maintenance in Patients With Newly Diagnosed Multiple Myeloma

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 09 Jan 2026

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At a glance

  • Drugs Bortezomib (Primary) ; Bortezomib (Primary) ; Dexamethasone (Primary) ; Lenalidomide (Primary) ; Melphalan (Primary) ; Melphalan (Primary) ; Cyclophosphamide; Prednisone
  • Indications Multiple myeloma
  • Focus Therapeutic Use
  • Acronyms EMN02/HOVON 95; HO95

Most Recent Events

  • 06 Jan 2026 Status changed from active, no longer recruiting to completed.
  • 21 Aug 2024 Planned End Date changed from 1 Apr 2024 to 1 Jan 2025.
  • 22 Nov 2023 This study has been completed in Austria, according to European Clinical Trials Database record.

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