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An open-label, randomized, single-center, 2-way cross-over interaction study, evaluating the effect of esomeprazole 20 mg/acetylsalicylic acid 81 mg on the pharmacodynamics and the pharmacokinetics of clopidogrel on days 1 and 9 in healthy volunteers

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An open-label, randomized, single-center, 2-way cross-over interaction study, evaluating the effect of esomeprazole 20 mg/acetylsalicylic acid 81 mg on the pharmacodynamics and the pharmacokinetics of clopidogrel on days 1 and 9 in healthy volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 22 Apr 2014

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At a glance

  • Drugs Aspirin/esomeprazole (Primary) ; Clopidogrel
  • Indications Cardiovascular disorders; NSAID-induced ulcer
  • Focus Pharmacodynamics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 28 Mar 2014 Results published in the American Journal of Cardiovascular Drugs.
    • 06 Oct 2011 Actual end date (Aug 2011) added as reported by ClinicalTrials.gov.
    • 06 Oct 2011 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov.

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