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A Phase I/II Study Evaluating the Safety and Efficacy of Adding a Single Prophylactic Donor Lymphocyte Infusion (DLI) of Natural Killer Cells Early After Nonmyeloablative, HLA-Haploidentical Hematopoietic Cell Transplantation - A Multicenter Trial.

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A Phase I/II Study Evaluating the Safety and Efficacy of Adding a Single Prophylactic Donor Lymphocyte Infusion (DLI) of Natural Killer Cells Early After Nonmyeloablative, HLA-Haploidentical Hematopoietic Cell Transplantation - A Multicenter Trial.

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Cell therapies; Cyclophosphamide; Fludarabine; Mycophenolate mofetil; Natural killer cell modulators; Tacrolimus; Tacrolimus
  • Indications Acute myeloid leukaemia; Bone marrow transplant rejection; Chronic lymphocytic leukaemia; Chronic myeloid leukaemia; Diffuse large B cell lymphoma; Hodgkin's disease; Mantle-cell lymphoma; Multiple myeloma; Myelodysplastic syndromes; Myeloproliferative disorders; Non-Hodgkin's lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions

    • Most Recent Events

    • 31 Jan 2020 Biomarkers information updated
    • 21 May 2013 Additional lead trIal centre added as reported by ClinicalTrials.gov.
    • 07 Jun 2012 Planned end date changed from 1 Oct 2013 to 1 Oct 2015 as reported by ClinicalTrials.gov.

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