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Phase II Study of Neoadjuvant Immune Biomarker Modulation With Cetuximab Followed by Adjuvant Therapy With Concurrent Chemoradiotherapy or Radiotherapy With or Without Cetuximab for Locally Advanced Head and Neck Squamous Cell Carcinoma.

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Trial Profile

Phase II Study of Neoadjuvant Immune Biomarker Modulation With Cetuximab Followed by Adjuvant Therapy With Concurrent Chemoradiotherapy or Radiotherapy With or Without Cetuximab for Locally Advanced Head and Neck Squamous Cell Carcinoma.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Jan 2023

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At a glance

  • Drugs Cetuximab (Primary) ; Carboplatin; Cisplatin
  • Indications Head and neck cancer; Squamous cell cancer
  • Focus Biomarker; Pharmacodynamics

    • Most Recent Events

    • 03 Jan 2023 Results of pooled analysis of three studies (NCT00779389, NCT01218048, NCT02473731) assessing response to neoadjuvant targeted therapy in operable head and neck cancer confers survival benefit, published in the Clinical Cancer Research.
    • 14 Aug 2018 Status changed from active, no longer recruiting to completed.
    • 07 Jun 2016 Results presented at the 52nd Annual Meeting of the American Society of Clinical Oncology

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