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A Phase I, Open-label, Multicentre, Dose Escalation Study to Assess the Safety and Tolerability, and Pharmacokinetics of AZD1480 in Asian Patients With Advanced Solid Malignancies and Asian Patients With Child-Pugh A to B7 Advanced Hepatocellular Carcinoma (HCC) in the Escalation Phase, Estimated Glomerular Filtration Rate(EGFR) or ROS Mutant NSCLC and Non-smokers With Lung Metastasis and Gastric Cancer and Solid Tumour With Biopsy Available in the Expansion Phase.

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Trial Profile

A Phase I, Open-label, Multicentre, Dose Escalation Study to Assess the Safety and Tolerability, and Pharmacokinetics of AZD1480 in Asian Patients With Advanced Solid Malignancies and Asian Patients With Child-Pugh A to B7 Advanced Hepatocellular Carcinoma (HCC) in the Escalation Phase, Estimated Glomerular Filtration Rate(EGFR) or ROS Mutant NSCLC and Non-smokers With Lung Metastasis and Gastric Cancer and Solid Tumour With Biopsy Available in the Expansion Phase.

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs AZD 1480 (Primary)
  • Indications Cancer metastases; Gastric cancer; Liver cancer; Solid tumours
  • Focus Adverse reactions

    • Most Recent Events

    • 01 Dec 2012 Status changed from suspended to discontinued as reported by ClinicalTrials.gov.
    • 09 Oct 2012 Status changed from recruiting to suspended as reported by ClinicalTrials.gov.
    • 26 Jul 2012 Official title amended, primary endpoint and additional lead trial investigators added as reported by ClinicalTrials.gov.
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