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Phase II, Multicenter, Open Label, Prospective to Evaluate Efficacy and Tolerance of a Chemoimmunotherapy With HyperCVAD or Vincristine/Dexamethasone Plus the Anti-CD22 Monovlonal Antobody Epratuzumab for the Treatment of Adult Relapsed/Refractory CD22+ B-Acute Lymphoblastic Leukaemia Patients : CHEPRALL Study, a GRAALL Study.

Trial Profile

Phase II, Multicenter, Open Label, Prospective to Evaluate Efficacy and Tolerance of a Chemoimmunotherapy With HyperCVAD or Vincristine/Dexamethasone Plus the Anti-CD22 Monovlonal Antobody Epratuzumab for the Treatment of Adult Relapsed/Refractory CD22+ B-Acute Lymphoblastic Leukaemia Patients : CHEPRALL Study, a GRAALL Study.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs Epratuzumab (Primary) ; Cyclophosphamide; Dexamethasone; Doxorubicin; Vincristine
  • Indications Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Therapeutic Use
  • Acronyms CHEPRALL
  • Most Recent Events

    • 26 Feb 2018 Status changed from recruiting to completed.
    • 06 Dec 2016 Results (n=31) presented at the 58th Annual Meeting and Exposition of the American Society of Hematology
    • 12 Nov 2015 Planned primary completion date changed from 1 Jan 2013 to 1 Dec 2016, as reported by ClinicalTrials.gov.

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