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An Open-label, Single-Sequence Study to Evaluate the Effects of Diltiazem, a Moderate CYP3A4/A5 Inhibitor, on the Pharmacokinetics and Pharmacodynamics of E5555 and Its Metabolites in Healthy Subjects.

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Trial Profile

An Open-label, Single-Sequence Study to Evaluate the Effects of Diltiazem, a Moderate CYP3A4/A5 Inhibitor, on the Pharmacokinetics and Pharmacodynamics of E5555 and Its Metabolites in Healthy Subjects.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs Atopaxar (Primary) ; Diltiazem
  • Indications Acute coronary syndromes; Angina pectoris; Coronary disorders; Hypertension
  • Focus Pharmacodynamics; Pharmacokinetics
  • Sponsors Eisai Inc

    • Most Recent Events

    • 14 Jan 2011 Actual end date (Dec 2010 ) added as reported by ClinicalTrials.gov.
    • 14 Jan 2011 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
    • 20 Dec 2010 New trial record

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