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Comparison of the pharmacokinetics and tolerability of amlodipine + valsartan, amlodipine + hydrochlorothiazide, valsartan + hydrochlorothiazide, and amlodipine + valsartan + hydrochlorothiazide in patients with hypertension.

Trial Profile

Comparison of the pharmacokinetics and tolerability of amlodipine + valsartan, amlodipine + hydrochlorothiazide, valsartan + hydrochlorothiazide, and amlodipine + valsartan + hydrochlorothiazide in patients with hypertension.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Apr 2012

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At a glance

  • Drugs Amlodipine (Primary) ; Hydrochlorothiazide (Primary) ; Valsartan (Primary)
  • Indications Hypertension
  • Focus Pharmacokinetics
  • Sponsors Novartis Pharmaceuticals Corporation
  • Most Recent Events

    • 25 Apr 2012 Population pharmacokinetic analysis of hydrochlorothiazide presented at the 113th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics.
    • 13 Jan 2011 New trial record
    • 17 Sep 2010 Results published in the Journal of Clinical Pharmacology.

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