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Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: A Randomised, Double-blind, Placebo Controlled, Parallel Group, Multi-centre, Multinational Trial With Stratification of Subject to Either 56 or 160 Weeks of Treatment Based on Pre-diabetes Status at Randomisation

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Trial Profile

Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: A Randomised, Double-blind, Placebo Controlled, Parallel Group, Multi-centre, Multinational Trial With Stratification of Subject to Either 56 or 160 Weeks of Treatment Based on Pre-diabetes Status at Randomisation

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 20 Dec 2021

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At a glance

  • Drugs Liraglutide (Primary)
  • Indications Obesity; Prediabetic state; Type 2 diabetes mellitus
  • Focus Registrational; Therapeutic Use
  • Acronyms SCALE; SCALE-Obesity and Pre-diabetes
  • Sponsors Novo Nordisk

Most Recent Events

  • 04 Sep 2020 Results of post-hoc analysis assessing association between body mass index and health-related quality of life in population with obesity and prediabetes from the 3-years of this SCALE study presented at the 2020 European and International Congress on Obesity
  • 07 Apr 2017 According to a Novo Nordisk media release, the US Food and Drug Administration (FDA) approved an updated product label for Saxenda (liraglutide) injection 3 mg. The label update is based on long term safety and efficacy data from this trial.
  • 27 Feb 2017 Results (n=2254) of 3 years of treatment with liraglutide in adults with prediabetes and a body-mass index of at least 30 kg/m2, or at least 27 kg/m2 with comorbidities, published in the lancet journal.

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