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A Phase I/II Study to Evaluate Safety, Tolerability, Pharmacokinetics and Efficacy of Resminostat (4SC-201) in Combination With a Second-line Treatment in Patients With K-ras Mutated Advanced Colorectal Carcinoma

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Trial Profile

A Phase I/II Study to Evaluate Safety, Tolerability, Pharmacokinetics and Efficacy of Resminostat (4SC-201) in Combination With a Second-line Treatment in Patients With K-ras Mutated Advanced Colorectal Carcinoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs Resminostat (Primary) ; Fluorouracil; Folinic acid; Irinotecan
  • Indications Colorectal cancer
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Acronyms SHORE
  • Sponsors 4SC

Most Recent Events

  • 02 Dec 2016 Results of biomarker analysis from SHELTER,SAPHIRE and SHORE trials presented at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics.
  • 31 Mar 2015 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
  • 21 Jan 2015 Planned End Date changed from 1 Jun 2014 to 1 Feb 2015 as reported by ClinicalTrials.gov.

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