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A Randomized Phase 2 Study of Ruxolitinib Efficacy and Safety in Combination With CApecitabine for Subjects With Recurrent or Treatment Refractory Metastatic Pancreatic Cancer (The RECAP Trial).

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Trial Profile

A Randomized Phase 2 Study of Ruxolitinib Efficacy and Safety in Combination With CApecitabine for Subjects With Recurrent or Treatment Refractory Metastatic Pancreatic Cancer (The RECAP Trial).

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Jan 2020

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At a glance

  • Drugs Ruxolitinib (Primary) ; Capecitabine
  • Indications Pancreatic cancer
  • Focus Proof of concept; Therapeutic Use
  • Acronyms RECAP
  • Sponsors Incyte Corporation

    • Most Recent Events

    • 27 Jan 2017 Status changed from active, no longer recruiting to completed.
    • 11 Feb 2016 Based on the interim results of JANUS 1 and the phase 2 sub-study in patients with metastatic colorectal cancer and CRP, ongoing Incyte-sponsored trials of ruxolitinib in solid tumors will be discontinued, including the phase 3 JANUS 2 study in pancreatic cancer, the Phase 2 sub-study in patients with metastatic colorectal cancer and low CRP, and the phase 2 studies in breast and lung cancer, according to an Incyte Corporation media release.
    • 29 Jan 2016 Planned End Date changed from 1 Dec 2015 to 1 Jun 2016 as reported by ClinicalTrials.gov.

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