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An Open-Label, Phase I/II, Dose-Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Patients With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma and in Combination With Endocrine Therapy in Patients With Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer

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Trial Profile

An Open-Label, Phase I/II, Dose-Escalation Study Evaluating the Safety and Tolerability of GDC-0032 in Patients With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma and in Combination With Endocrine Therapy in Patients With Locally Advanced or Metastatic Hormone Receptor-Positive Breast Cancer

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 02 Aug 2024

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At a glance

  • Drugs Taselisib (Primary) ; Fulvestrant; Letrozole; Midazolam
  • Indications Advanced breast cancer; Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma; Solid tumours
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Sponsors Genentech

Most Recent Events

  • 31 Jul 2024 Status changed from completed to discontinued.
  • 03 Sep 2021 Status changed from active, no longer recruiting to completed.
  • 04 Nov 2020 Results published in the Clinical Cancer Research

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