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An Open-Label, Non-Randomized Study of Pharmacokinetic Interactions Between Depo-Medroxyprogesterone Acetate (DMPA) and Lopinavir/Ritonavir (LPV/r) and of the Effects of DMPA on Cellular Immunity and Regulation in HIV-Infected Women

Trial Profile

An Open-Label, Non-Randomized Study of Pharmacokinetic Interactions Between Depo-Medroxyprogesterone Acetate (DMPA) and Lopinavir/Ritonavir (LPV/r) and of the Effects of DMPA on Cellular Immunity and Regulation in HIV-Infected Women

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs Lopinavir/ritonavir (Primary) ; Medroxyprogesterone (Primary)
  • Indications HIV-1 infections; Pregnancy
  • Focus Pharmacokinetics
  • Most Recent Events

    • 20 Jun 2021 Results of a population pharmacokinetic analysis of data pooled from three ACTG studies (A5093, A5283 and A5338) published in the Clinical Pharmacology and Therapeutics
    • 11 Mar 2020 Results (n=138) of pooled analysis from three clinical studies: ACTG A5093, ACTG A5283 and ACTG A5338 were presented at the 27th Conference on Retroviruses and Opportunistic Infections
    • 24 Jan 2013 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov.
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