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A Randomized, Open-label, Phase 3 Study of Carfilzomib vs Best Supportive Care in Subjects With Relapsed and Refractory Multiple Myeloma.

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Trial Profile

A Randomized, Open-label, Phase 3 Study of Carfilzomib vs Best Supportive Care in Subjects With Relapsed and Refractory Multiple Myeloma.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 10 Oct 2022

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At a glance

  • Drugs Carfilzomib (Primary) ; Cyclophosphamide; Dexamethasone; Prednisolone
  • Indications Multiple myeloma
  • Focus Registrational; Therapeutic Use
  • Acronyms FOCUS
  • Sponsors Amgen; Onyx Pharmaceuticals

    • Most Recent Events

    • 01 Oct 2022 Results of post-hoc pooled analysis assessing cardiovascular risk factors and cardiovascular disease data from four clinical studies: ASPIRE, ARROW, FOCUS, ENDEAVOR published in the Clinical Lymphoma, Myeloma & Leukemia
    • 23 Nov 2015 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
    • 05 Mar 2015 Planned End Date changed from 1 Jan 2015 to 1 Dec 2015 as reported by ClinicalTrials.gov record.

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