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A Randomized, Open-Label, Phase 3 Study to Compare Long-Term Safety and Tolerability of the TAK-491 and Chlorthalidone Fixed-Dose Combination Versus Olmesartan Medoxomil and Hydrochlorothiazide Fixed-Dose Combination in Hypertensive Subjects With Moderate Renal Impairment.

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Trial Profile

A Randomized, Open-Label, Phase 3 Study to Compare Long-Term Safety and Tolerability of the TAK-491 and Chlorthalidone Fixed-Dose Combination Versus Olmesartan Medoxomil and Hydrochlorothiazide Fixed-Dose Combination in Hypertensive Subjects With Moderate Renal Impairment.

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 08 Nov 2021

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At a glance

  • Drugs Azilsartan medoxomil/chlortalidone (Primary) ; Olmesartan medoxomil/hydrochlorothiazide
  • Indications Essential hypertension
  • Focus Adverse reactions; Registrational
  • Sponsors Takeda; Takeda Global Research and Development Center

    • Most Recent Events

    • 04 Mar 2018 Results published in the Journal of Clinical Hypertension (Greenwich)
    • 04 Mar 2018 Results assessing long term efficacy and tolerability published in the Journal of Clinical Hypertension (Greenwich)
    • 05 Oct 2012 Planned number of patients changed from 154 to 350 as reported by European Clinical Trials Database.

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