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A randomised trial to investigate the effect of Elafin on myocardial injury and inflammation in coronary artery bypass surgery.

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Trial Profile

A randomised trial to investigate the effect of Elafin on myocardial injury and inflammation in coronary artery bypass surgery.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Oct 2022

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At a glance

  • Drugs Tiprelestat (Primary)
  • Indications Myocardial reperfusion injury
  • Focus Proof of concept; Therapeutic Use
  • Acronyms EMPIRE

Most Recent Events

  • 26 Aug 2015 Results published in the Heart.
  • 26 Aug 2015 Primary endpoint (Area under the curve (AUC) for plasma troponin I concentration over 48 hours.) has not been met as per results published in the Heart.
  • 13 Mar 2015 Interim results (significant reduction in troponin I after 6 hours) published in Proteo, Inc Media Release.

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