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A Phase I Dose Escalation Trial of BI 836845 Administered Intravenously Once Every Three Weeks in Patients With Advanced Solid Tumours During Escalation and Weekly in Selected Tumour Types During Expansion, With Repeated Administrations in Patients Showing Clinical Benefit

Trial Profile

A Phase I Dose Escalation Trial of BI 836845 Administered Intravenously Once Every Three Weeks in Patients With Advanced Solid Tumours During Escalation and Weekly in Selected Tumour Types During Expansion, With Repeated Administrations in Patients Showing Clinical Benefit

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Mar 2020

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At a glance

  • Drugs Xentuzumab (Primary)
  • Indications Ewing's sarcoma; Neuroectodermal tumours; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Boehringer Ingelheim Pharmaceuticals
  • Most Recent Events

    • 12 Mar 2020 Results from NCT01403974 and NCT01317420; assessing the maximum-tolerated/relevant biological dose (MTD/RBD), safety, pharmacokinetics, pharmacodynamics, and activity of xentuzumab in advanced/metastatic solid cancers, published in the British Journal of Cancer
    • 25 Feb 2016 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
    • 14 Jan 2016 Status changed from recruiting to active, no longer recruiting as per ClinicalTrials.gov record.

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