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Effect of Roflumilast on Exacerbation Rate in Patients With COPD Treated With Fixed Combinations of LABA and ICS. A 52-week, Randomised Double-blind Trial With Roflumilast 500 microg Versus Placebo The REACT Trial

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Effect of Roflumilast on Exacerbation Rate in Patients With COPD Treated With Fixed Combinations of LABA and ICS. A 52-week, Randomised Double-blind Trial With Roflumilast 500 microg Versus Placebo The REACT Trial

Status: Completed
Phase of Trial: Phase III/IV

Latest Information Update: 31 Jan 2019

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At a glance

  • Drugs Roflumilast (Primary)
  • Indications Chronic obstructive pulmonary disease
  • Focus Registrational; Therapeutic Use
  • Acronyms REACT
  • Sponsors Takeda; Takeda Pharma

    • Most Recent Events

    • 15 May 2018 Pooled analysis results from REACT and RE2SPOND studies (n=4287) were published in the American Journal of Respiratory and Critical Care Medicine
    • 24 May 2017 Results of pooled analysis from REACT and RE2SPOND studies evaluating the efficacy of roflumilast in the overall population and in patients with a history of COPD-related hospitalization presented at the 113th International Conference of the American Thoracic Society.
    • 16 Jun 2014 According to the ClinicalTrials.gov record, status changed from active, no longer recruiting to completed.

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