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A Randomized, Double Masked, Active Controlled, Phase III Study of the Efficacy and Safety of Repeated Doses of Intravitreal VEGF Trap-Eye in Subjects With Diabetic Macular Edema

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A Randomized, Double Masked, Active Controlled, Phase III Study of the Efficacy and Safety of Repeated Doses of Intravitreal VEGF Trap-Eye in Subjects With Diabetic Macular Edema

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 27 Jul 2023

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At a glance

  • Drugs Aflibercept (Primary)
  • Indications Diabetic macular oedema
  • Focus Registrational; Therapeutic Use
  • Acronyms VIVID-DME
  • Sponsors Bayer; Bayer HealthCare

    • Most Recent Events

    • 01 Jul 2023 Results of post-hoc analysis of two studies VISTA & VIVID assessing time to, cumulative incidence of, and functional benefit of achieving sustained ≥2-step Diabetic Retinopathy Severity Scale (DRSS) improvement in diabetic macular oedema, published in the Eye.
    • 09 Jun 2015 Pooled results of sub-analysis of this and VISTA-DME trials (assessing visual outcome) presented at the 75th Annual Scientific Sessions of the American Diabetes Association.
    • 12 May 2015 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.

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