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Open Label, Dose Escalation Study of 4SC-202 in Patients With Advanced Hematologic Malignancies: First-In-Man Study of a Newly Developed, Oral Histone Deacetylase Inhibitor

Trial Profile

Open Label, Dose Escalation Study of 4SC-202 in Patients With Advanced Hematologic Malignancies: First-In-Man Study of a Newly Developed, Oral Histone Deacetylase Inhibitor

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Domatinostat (Primary)
  • Indications Acute myeloid leukaemia; Chronic lymphocytic leukaemia; Haematological malignancies; Lymphoma; Multiple myeloma; Myelodysplastic syndromes; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Acronyms TOPAS
  • Sponsors 4SC
  • Most Recent Events

    • 21 Mar 2016 Results published in 4SC AG media release.
    • 07 May 2015 According to a 4SC media release, final data report is expected to be published in mid-2015.
    • 31 Mar 2015 Status changed from active, no longer recruiting to completed as per ClinicalTrials.gov record.

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