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An Open-Label, Dose-Escalation, Phase 1/2 Study of the Oral Form of IXAZOMIB (MLN9708), a Next-Generation Proteasome Inhibitor, Administered in Combination With a Standard Care Regimen of Melphalan and Prednisone in Patients With Newly Diagnosed Multiple Myeloma Requiring Systemic Treatment

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An Open-Label, Dose-Escalation, Phase 1/2 Study of the Oral Form of IXAZOMIB (MLN9708), a Next-Generation Proteasome Inhibitor, Administered in Combination With a Standard Care Regimen of Melphalan and Prednisone in Patients With Newly Diagnosed Multiple Myeloma Requiring Systemic Treatment

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 12 Dec 2022

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At a glance

  • Drugs Ixazomib (Primary) ; Melphalan; Prednisone
  • Indications Multiple myeloma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Takeda Oncology

    • Most Recent Events

    • 22 Dec 2017 Status changed from active, no longer recruiting to completed.
    • 12 Dec 2017 Results of an integrated analysis from NCT01217957, NCT01383928, NCT01335685 and NCT02046070 studies, presented at the 59th Annual Meeting and Exposition of the American Society of Hematology
    • 25 Jun 2017 Results (n=61) assessing safety and efficacy, presented at the 22nd Congress of the European Haematology Association.

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