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Phase II Study of Lenalidomide to Repair Immune Synapse Response and Humoral Immunity in Early-Stage, Asymptomatic Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) With High-Risk Genomic Features.

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Trial Profile

Phase II Study of Lenalidomide to Repair Immune Synapse Response and Humoral Immunity in Early-Stage, Asymptomatic Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) With High-Risk Genomic Features.

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Jul 2024

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At a glance

  • Drugs Lenalidomide (Primary) ; Pneumococcal 13-valent CRM197 vaccine conjugate (Primary)
  • Indications Chronic lymphocytic leukaemia; Pneumococcal infections
  • Focus Pharmacodynamics

    • Most Recent Events

    • 12 Dec 2023 Long term results (N=49) evaluating the impact of Lenalidomide early treatment on chronic lymphocytic leukemia, complicating infections (INF), and second neoplasms (SN). presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 19 Jan 2022 Planned End Date changed from 31 Dec 2021 to 31 Dec 2024.
    • 19 Jan 2022 Planned primary completion date changed from 31 Dec 2021 to 31 Dec 2024.

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