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A Randomized, Double Blind, Placebo Controlled Phase 2 Study To Assess The Immune Response Following Administration Of Influenza And Pneumococcal Vaccines To Subjects With Rheumatoid Arthritis Receiving Cp-690,550 Or Placebo Cp-690,550 With And Without Background Methotrexate.

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A Randomized, Double Blind, Placebo Controlled Phase 2 Study To Assess The Immune Response Following Administration Of Influenza And Pneumococcal Vaccines To Subjects With Rheumatoid Arthritis Receiving Cp-690,550 Or Placebo Cp-690,550 With And Without Background Methotrexate.

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Feb 2025

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At a glance

  • Drugs Tofacitinib (Primary) ; Influenza virus vaccine; Methotrexate; Pneumococcal vaccine
  • Indications Influenza A virus H1N1 subtype; Influenza A virus H3N2 subtype; Influenza virus infections; Pneumococcal infections; Rheumatoid arthritis
  • Focus Pharmacodynamics

    • Most Recent Events

    • 31 Jan 2017 Long term safety results (n=6194 data cut off 31 Mar 2015) of 2 phase I, 9 phase II, 6 phase III and 2 long term extension studies (NCT01262118, NCT01484561, NCT00147498, NCT00413660, NCT00550446, NCT00603512, NCT00687193, NCT01164579, NCT00976599, NCT01059864, NCT01359150, NCT00960440, NCT00847613, NCT00814307, NCT00856544, NCT00853385, NCT01039688, NCT00413699, NCT00661661) in adult patients with active Rheumatoid arthritis published in the Annals of the Rheumatic Diseases
    • 15 Jun 2013 Results presented at the 14th Annual Congress of the European League Against Rheumatism.
    • 13 May 2013 Data will be presented at the European League Against Rheumatism (EULAR) 2013 Annual Meeting, according to a Pfizer media release.

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