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Multicentre randomized phase II study of neoadjuvant trastuzumab plus docetaxel with and without bevacizumab and trastuzumab plus docetaxel plus non-pegylated liposome-encapsulated doxorubicin (NPLD) with and without bevacizumab in HER2-positive early breast cancer [Multizentrisch randomisierte Phase II Studie für neoadjuvantes Trastuzumab plus Docetaxel plus nicht pegyliertes liposomal verkapseltes Doxorubicincitrat (NPLD) mit und ohne Bevacizumab bei HER2-positivem frühem Mammakarzinom].

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Trial Profile

Multicentre randomized phase II study of neoadjuvant trastuzumab plus docetaxel with and without bevacizumab and trastuzumab plus docetaxel plus non-pegylated liposome-encapsulated doxorubicin (NPLD) with and without bevacizumab in HER2-positive early breast cancer [Multizentrisch randomisierte Phase II Studie für neoadjuvantes Trastuzumab plus Docetaxel plus nicht pegyliertes liposomal verkapseltes Doxorubicincitrat (NPLD) mit und ohne Bevacizumab bei HER2-positivem frühem Mammakarzinom].

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Bevacizumab (Primary) ; Doxorubicin liposomal (Primary) ; Docetaxel; Trastuzumab
  • Indications Early breast cancer; HER2 positive breast cancer; Male breast cancer
  • Focus Adverse reactions

Most Recent Events

  • 12 May 2014 Status changed from active, no longer recruiting to completed as reported by ClinicalTrials.gov record.
  • 23 Aug 2013 Status changed from recruiting to active, no longer recruiting as reported by ClinicalTrials.gov.
  • 13 Sep 2011 Status changed from not yet recruiting to recruiting as reported by ClinicalTrials.gov.

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