Trial Profile

A Phase I, Randomized, Open-Label, Active- and Placebo-Controlled Parallel Group Study of the Effect of Subcutaneous and Intravenous Methylnaltrexone on CYP450 2D6 Activity in Healthy Extensive Metabolizers of Dextromethorphan.

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 16 May 2019

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At a glance

Drugs Methylnaltrexone bromide (Primary) ; Methylnaltrexone bromide (Primary) ; Paroxetine
Indications Constipation
Focus Pharmacokinetics
Sponsors Progenics Pharmaceuticals

17 Jul 2011 Additional lead trial centre identified as reported by ClinicalTrials.gov.
09 Jun 2011 New trial record

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