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A Phase II Neo-adjuvant Study Assessing TCH (Docetaxel, Carboplatin and Trastuzumab) and TCHL (Docetaxel, Carboplatin, Trastuzumab and Lapatinib) in HER-2 Positive Breast Cancer Patients

Trial Profile

A Phase II Neo-adjuvant Study Assessing TCH (Docetaxel, Carboplatin and Trastuzumab) and TCHL (Docetaxel, Carboplatin, Trastuzumab and Lapatinib) in HER-2 Positive Breast Cancer Patients

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 14 Feb 2023

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At a glance

  • Drugs Lapatinib (Primary) ; Trastuzumab (Primary) ; Carboplatin; Docetaxel
  • Indications Advanced breast cancer; Early breast cancer; HER2 positive breast cancer
  • Focus Therapeutic Use
  • Acronyms TCHL-Phase-II

Most Recent Events

  • 01 Jun 2021 Results performing tumour-associated lymphocytes analysis and T-cell analysis by immunohistochemistry on the pretreatment and on-treatment samples from NCT01485926, published in the Breast Cancer Research and Treatment
  • 29 Oct 2020 Results published in the Clinical Cancer Research
  • 24 Jun 2020 Results assessing effects of neo-adjuvant chemotherapy on the phenotype and cytotoxic capacity of peripheral blood mononuclear cells breast cancer patients presented at the 111th Annual Meeting of the American Association for Cancer Research - II

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