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A multicentre, multinational, randomised, double-blind, pilot, ascending dose for non responder, parallel group study on the therapeutic efficacy and safety of o.d. Zofenopril 30 mg plus HCTZ 12.5 mg vs. Irbersartan 150 mg plus HCTZ 12.5 mg in elderly subjects (age > 65 years) affected by Isolated Systolic Hypertension never treated or non responder to previous antihypertensive therapy (monotherapy or association of maximum two treatments).

Trial Profile

A multicentre, multinational, randomised, double-blind, pilot, ascending dose for non responder, parallel group study on the therapeutic efficacy and safety of o.d. Zofenopril 30 mg plus HCTZ 12.5 mg vs. Irbersartan 150 mg plus HCTZ 12.5 mg in elderly subjects (age > 65 years) affected by Isolated Systolic Hypertension never treated or non responder to previous antihypertensive therapy (monotherapy or association of maximum two treatments).

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 16 Mar 2015

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At a glance

  • Drugs Zofenopril (Primary) ; Hydrochlorothiazide; Irbesartan
  • Indications Isolated systolic hypertension
  • Focus Therapeutic Use
  • Sponsors Istituto Lusofarmaco

Most Recent Events

  • 26 Jul 2013 Status changed from recruiting to completed as reported by European Clinical Trials Database.
  • 23 Jun 2011 New trial record

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