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A Multi-Center, Phase 1, Open-Label Evaluation Of The Effect Of PF-00547659 (Anti Madcam Monoclonal Antibody) On Cerebrospinal Fluid (CSF) Lymphocytes In Volunteers With Crohns Disease Or Ulcerative Colitis Who Are Anti-TNFInadequate Responders (TOSCA)

Trial Profile

A Multi-Center, Phase 1, Open-Label Evaluation Of The Effect Of PF-00547659 (Anti Madcam Monoclonal Antibody) On Cerebrospinal Fluid (CSF) Lymphocytes In Volunteers With Crohns Disease Or Ulcerative Colitis Who Are Anti-TNFInadequate Responders (TOSCA)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Ontamalimab (Primary)
  • Indications Crohn's disease; Ulcerative colitis
  • Focus Pharmacodynamics
  • Acronyms TOSCA
  • Sponsors Pfizer

Most Recent Events

  • 14 Jun 2016 Results published in a Shire media release.
  • 17 May 2016 Results presented at the IMMUNOLOGY 2016 American Association of Immunologists Annual Meeting
  • 21 Jan 2016 Status changed from active, no longer recruiting to completed, as per ClinicalTrials.gov record.

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