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A Phase I Open-Label, 2-Part, 3-Cohort, Single-Centre Study to Assess the Concentration of Avibactam and Ceftazidime in Epithelial Lining Fluid and Plasma Using at Least Two Different Dosing Regimens in Healthy Volunteers.

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A Phase I Open-Label, 2-Part, 3-Cohort, Single-Centre Study to Assess the Concentration of Avibactam and Ceftazidime in Epithelial Lining Fluid and Plasma Using at Least Two Different Dosing Regimens in Healthy Volunteers.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 01 Aug 2018

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At a glance

  • Drugs Avibactam/ceftazidime (Primary)
  • Indications Gram-negative infections; Intra-abdominal infections; Nosocomial infections; Urinary tract infections
  • Focus Pharmacokinetics
  • Sponsors AstraZeneca

    • Most Recent Events

    • 27 Jul 2018 Results published in the Drugs in R and D
    • 25 Apr 2017 Results assessing population pharmacokinetic modelling of ceftazidime and avibactam in healthy volunteers presented at the 27th European Congress of Clinical Microbiology and Infectious Diseases.
    • 13 Sep 2013 Results presented at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy.

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