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A Phase 1, Open-Label, Study of the Effect of Cimetidine, a Known Inhibitor of Active Renal Secretion, on the Single-Dose Pharmacokinetics of Intravenously-Administered Methylnaltrexone in Healthy Adults

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Trial Profile

A Phase 1, Open-Label, Study of the Effect of Cimetidine, a Known Inhibitor of Active Renal Secretion, on the Single-Dose Pharmacokinetics of Intravenously-Administered Methylnaltrexone in Healthy Adults

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 15 May 2019

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At a glance

  • Drugs Methylnaltrexone bromide (Primary) ; Cimetidine
  • Indications Constipation; Pancreatic cancer
  • Focus Pharmacokinetics
  • Sponsors Progenics Pharmaceuticals; Salix Pharmaceuticals

Most Recent Events

  • 21 Jul 2011 New trial record

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