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A Phase 2 Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL)

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Trial Profile

A Phase 2 Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 28 Oct 2020

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At a glance

  • Drugs Brentuximab vedotin (Primary) ; Rituximab
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Non-Hodgkin's lymphoma; Peripheral T-cell lymphoma; Post-transplant lymphoproliferative disorder
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Seagen; Seattle Genetics

    • Most Recent Events

    • 04 Jun 2019 Results assessing CD30 expression level to predict response to brentuximab vedotin by using data from five studies including this study presented at the 55th Annual Meeting of the American Society of Clinical Oncology.
    • 03 Jun 2019 Results of an exploratory analysis using data integrated from 275 patients with peripheral T-cell lymphoma, cutaneous T-cell lymphoma, and B-cell lymphoma treated with Brentuximab vedotin from 5 prospective clinical trials (NCT01421667, NCT02588651, NCT01578499, NCT01352520, NCT01396070) presented in a Seattle Genetics media release.
    • 19 Oct 2015 Data of DLBCL patients who received single agent ADCETRIS or in combination with Rituxan every three weeks were published in a Seattle Genetics media release.

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