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Multi-centric Randomized Phase II Study of Pre-operative Afatinib (BIBW2992) Aiming at Identifying Predictive and Pharmacodynamic Biomarkers of Biological Activity and Efficacy in Untreated Non-metastatic Head and Neck Squamous Cell Carcinoma Patients

Trial Profile

Multi-centric Randomized Phase II Study of Pre-operative Afatinib (BIBW2992) Aiming at Identifying Predictive and Pharmacodynamic Biomarkers of Biological Activity and Efficacy in Untreated Non-metastatic Head and Neck Squamous Cell Carcinoma Patients

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 19 May 2022

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At a glance

  • Drugs Afatinib (Primary)
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Biomarker; Pharmacodynamics; Therapeutic Use
  • Acronyms PREDICTOR

Most Recent Events

  • 13 Apr 2022 Results presented at the 113th Annual Meeting of the American Association for Cancer Research
  • 01 Feb 2022 Status changed from active, no longer recruiting to completed.
  • 22 Mar 2021 Planned End Date changed from 1 Feb 2015 to 1 Dec 2021.

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