A Phase 1a/1b, Multi-center, Open-label, Dose Finding Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the Pleiotropic Pathway Modifier (PPM) CC-122 Administered Orally to Subjects With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myeloma

Trial Profile

A Phase 1a/1b, Multi-center, Open-label, Dose Finding Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of the Pleiotropic Pathway Modifier (PPM) CC-122 Administered Orally to Subjects With Advanced Solid Tumors, Non-Hodgkin's Lymphoma, or Multiple Myeloma

Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 03 Jul 2018

At a glance

  • Drugs Avadomide (Primary)
  • Indications CNS cancer; Diffuse large B cell lymphoma; Glioblastoma; Gliosarcoma; Liver cancer; Mantle-cell lymphoma; Multiple myeloma; Non-Hodgkin's lymphoma; Oligodendroglioma; Solid tumours
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Sponsors Celgene Corporation
  • Most Recent Events

    • 22 Jun 2018 Planned End Date changed from 29 Oct 2018 to 1 Aug 2019.
    • 22 Jun 2018 Planned primary completion date changed from 29 Oct 2018 to 1 Aug 2019.
    • 28 Feb 2018 Status changed from recruiting to active, no longer recruiting.
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