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Influence of OATP1B1 and CYP2C9 Genotypes on the Pharmacokinetics of Steady State Bosentan Before and During CYP3A4-inhibition by Clarithromycin

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Trial Profile

Influence of OATP1B1 and CYP2C9 Genotypes on the Pharmacokinetics of Steady State Bosentan Before and During CYP3A4-inhibition by Clarithromycin

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 18 Sep 2021

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At a glance

  • Drugs Bosentan; Clarithromycin
  • Indications Bacterial infections
  • Focus Pharmacogenomic; Pharmacokinetics

Most Recent Events

  • 31 May 2017 Biomarkers information updated
  • 01 Dec 2012 Status changed from recruiting to completed as reported by ClinicalTrials.gov.
  • 02 Sep 2011 New trial record

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