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Cost-effectiveness of CYP2C19 guided treatment with antiplatelet drugs in patients with ST-segment-elevation myocardial infarction undergoing immediate percutaneous coronary intervention with stent implantation: Optimization of treatment.

Trial Profile

Cost-effectiveness of CYP2C19 guided treatment with antiplatelet drugs in patients with ST-segment-elevation myocardial infarction undergoing immediate percutaneous coronary intervention with stent implantation: Optimization of treatment.

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 07 Nov 2021

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At a glance

  • Drugs Clopidogrel (Primary) ; Prasugrel (Primary) ; Ticagrelor (Primary) ; Aspirin
  • Indications Acute coronary syndromes; Coronary artery restenosis; Myocardial infarction; Stent thrombosis
  • Focus Adverse reactions; Pharmacogenomic; Therapeutic Use
  • Acronyms POPGenetics; POPular Genetics

Most Recent Events

  • 07 Sep 2021 Results assessing cost effectiveness of a genotype-guided strategy compared with standard treatment with ticagrelor or prasugrel, published in the American Journal of Cardiovascular Drugs.
  • 01 Jul 2021 Results of a pre-specified sub analysis (n=991) from the POPular Genetics and POPular Age trials assessing the effect of CYP2C19 loss-of-function alleles in clopidogrel treated elderly patients, published in the International Journal of Cardiology.
  • 17 May 2021 Results (N=4480) of Bayesian analysis of randomized clinical trials (RCTs) to assess the role of genotype-guided P2Y12 inhibitor therapy after PCI using data from TAILOR-PCI trial) and 2) informative priors (derived from ADAPT, POPular Genetics, IAC-PCI, PHARMCLO RCTs presented at the 70th Annual Scientific Session of the American College of Cardiology

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