Trial Profile

A Phase I Lead-In to a 2x2x2 Factorial Trial of Temozolomide, Memantine, Mefloquine, and Metformin as Post-Radiation Adjuvant Therapy of Glioblastoma Multiforme

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 13 May 2025

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At a glance

Drugs Mefloquine (Primary) ; Memantine (Primary) ; Metformin (Primary) ; Temozolomide (Primary)
Indications Glioblastoma; Gliosarcoma
Focus Adverse reactions

Most Recent Events

07 May 2025 Status changed from active, no longer recruiting to discontinued.
08 Feb 2024 Planned End Date changed from 30 Sep 2024 to 30 Sep 2025.
08 Feb 2024 Planned primary completion date changed from 30 Sep 2024 to 30 Sep 2025.

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