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A Phase I Lead-In to a 2x2x2 Factorial Trial of Temozolomide, Memantine, Mefloquine, and Metformin as Post-Radiation Adjuvant Therapy of Glioblastoma Multiforme

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Trial Profile

A Phase I Lead-In to a 2x2x2 Factorial Trial of Temozolomide, Memantine, Mefloquine, and Metformin as Post-Radiation Adjuvant Therapy of Glioblastoma Multiforme

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 15 Feb 2024

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At a glance

  • Drugs Mefloquine (Primary) ; Memantine (Primary) ; Metformin (Primary) ; Temozolomide (Primary)
  • Indications Glioblastoma; Gliosarcoma
  • Focus Adverse reactions

    • Most Recent Events

    • 08 Feb 2024 Planned End Date changed from 30 Sep 2024 to 30 Sep 2025.
    • 08 Feb 2024 Planned primary completion date changed from 30 Sep 2024 to 30 Sep 2025.
    • 07 Feb 2024 Planned End Date changed from 30 Sep 2023 to 30 Sep 2024.

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