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A Phase 2, Randomized Study to Evaluate the Efficacy and Safety of MEDI-546 in Subjects With Systemic Lupus Erythematosus

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Trial Profile

A Phase 2, Randomized Study to Evaluate the Efficacy and Safety of MEDI-546 in Subjects With Systemic Lupus Erythematosus

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Dec 2022

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At a glance

  • Drugs Anifrolumab (Primary)
  • Indications Systemic lupus erythematosus
  • Focus Registrational; Therapeutic Use
  • Acronyms MUSE
  • Sponsors MedImmune

    • Most Recent Events

    • 04 Jun 2022 Results of a pooled analysis assessing hypersensitivity profile of anifrolumab and need for pretreatment from following clinical studies: MUSE, TULIP-1, and TULIP-2 presented at the 23rd Annual Congress of the European League Against Rheumatism
    • 17 May 2022 Results assessing he degree of concordance between BICLA and SRI(4) across anifrolumab trials ( TULIP-1, TULIP-2 and MUSE ) published in the Annals of the Rheumatic Diseases.
    • 16 Feb 2022 According to an AstraZeneca media release, Saphnelo (anifrolumab) has been approved in the European Union as an add-on therapy for the treatment of adult patients with moderate to severe, active autoantibody-positive systemic lupus erythematosus (SLE), despite receiving standard therapy.

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